girk|Activation and inhibition of G protein,andrea botez age

G protein-gated inwardly rectifying potassium (GIRK) channels hyperpolarize neurons in response to activation of many different G protein-coupled receptors and thus control the excitability of neurons through GIRK-mediated self-inhibition, slow synaptic potentials and volume transmission.

Four G protein gated inwardly-rectifying potassium (GIRK) channel subunits have been identified in mammals: GIRK1, GIRK2, GIRK3, and GIRK4. The GIRK subunits come together to form GIRK ion channels.

G-protein-gated inwardly rectifying K + (GIRK) channels play a key role in maintaining resting membrane potential, cell excitability and inhibitory neurotransmission.

Andrea Cecilia Cristina Botez [1] (/ ˈ b oʊ t ɛ z / BOH-tez; born April 6, 2002) is a Canadian chess player, commentator, DgirkJ [2] and internet personality. [3] She is mostly known as part of the BotezLive Twitch channel with her sister Alexandra Botez .

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